Amaryl MP (glimepiride, metformin, pioglitazone) is a medication predominantly used to treat type 2 diabetes. Some patients who do not have diabetes buy Amaryl MP to help manage cholesterol levels or reduce risk of heart attack or stroke, but these cases are rare when diabetes is not present.

The medication is effective due to its three active ingredients, which are:

• Glimepiride promotes insulin production by the pancreas, lowering blood sugar as the new, additional insulin converts it to energy or stores it in tissues.
• Metformin lowers blood sugar by reducing its production in the liver, inhibiting glucose absorption, and increasing glucose uptake by muscle and fat.
• Pioglitazone reduces insulin resistance and further inhibits insulin production by the liver, further reducing blood sugar.

Note that all of these three ingredients can be bought independently, and not all type 2 diabetics require three medications to control blood glucose; patients should only buy Amaryl MP with doctor approval, usually after one or two medications have failed to produce good results.

This medication will provide little to no benefit in type 1 diabetics. It should not be administered to patients with diabetic ketoacidosis.

Parents should not administer Amaryl MP to children below age 16 without explicit doctor approval. Dosage modifications are likely required for younger patients, and Amaryl MP's smallest dose is likely too high.

What to Expect from Treatment

The majority of patients who buy Amaryl MP simply take one tablet per day, usually in the morning with breakfast. Taking each dose with a meal is strongly recommended.

Maximum benefit is reached between one and two weeks. Patients are usually started on lower doses, and dosage is increased only after one to two weeks have passed. Hypoglycemia---low blood sugar---is a real risk when treatment begins or when dosage is increased; monitoring blood sugar closely at the start of treatment or following dosage adjustments is critical.

The majority of patients who buy Amaryl MP are also given recommended lifestyle changes, including dietary improvements, regular exercise plans, quitting smoking, avoiding stress, and so forth. Many of these changes can be quite difficult to undertake at the start, but patients are strongly encouraged to do so---in the vast majority of cases, lifestyle changes are the only way to minimize or eliminate dependency on medication to manage blood sugar.

Patients who take Amaryl MP, particularly if lifestyle changes are also made, are better able to manage blood sugar. Keeping blood sugar in healthy ranges will slow or stop progression of type 2 diabetes, reducing or eliminating risks of serious complications---including blindness, loss of limbs, kidney failure, and so forth. Patients are better able to live long, healthy lives while retaining their independence.

Dosage & Administration

Amaryl MP comes in tablets, which, as mentioned above, are usually taken just once per day. Type 2 diabetes is a complex condition, as is treating it with three medications; for best results, a doctor should be involved. A doctor can help determine the ideal dosage as well as monitor for developing side effects from both Amaryl MP and diabetes itself. While we recognize that many patients prefer to self-diagnose and treat, doing so with this medication is not recommended.

Standard treatment guidelines are:

• Patients are started on low doses of 1 mg/500 mg/15 mg glimepiride/metformin/pioglitazone.
• Treatment should continue for about two weeks for maximum benefit to be seen.
• After two weeks, dosage may be increased, if needed, in small increments.
• Blood sugar should be monitored closely at the start of treatment and following any dosage adjustments.

Doctor instructions may vary to some degree for each individual, and doctor instructions should be followed.

Regular doctor checkups should also be scheduled and attended for monitoring purposes. Not all side effects are detectable by the patient until very severe.

Potential Side Effects

Most patients who buy Amaryl MP experience only minimal side effects, which usually aren't severe and should stop occurring within the first few weeks of treatment as the body adjusts. Commonly experienced are:

• Bloating
• Gas
• Diarrhea
• Constipation
• Heartburn
• Gastrointestinal discomfort
• Headache
• Mild dizziness
• Muscle aches
• Swelling of the throat

The above are not cause for concern unless severe or persistant.

Side effects which warrant medical attention include:

• Severe gastrointestinal pain
• Severe itching
• Chest pain
• Hypoglycemia

All patients who buy Amaryl MP should be aware that all three of the active ingredients put patients at risk of hypoglycemia. Serious effects are usually avoidable if blood sugar is monitored closely. All patients should be aware of, and alert for, symptoms. A doctor should cover this risk, and there is an abundance of information online.

There are also a couple of controversial risks associated with glimepiride and pioglitazone, which are pancreatic damage and bladder cancer. Some studies indicate patients are at increased risk, while other studies indicate no such risks. Millions of patients around the globe take Amaryl MP with no such issues, so if these conditions are associated with Amaryl MP they are very rare. More information can be found online; those with a history---including family history---of pancreatic or bladder conditions may want to look into it more closely.

Other side effects not detectable by the patient include low blood cell counts, altered liver or kidney enzymes, impaired bile flow, and so forth. A doctor should periodically screen for these. Medical staff should be made aware that Amaryl MP is being taken prior to performing laboratory tests for unrelated reasons.

Experience the Kiwi Drug Difference

Patients buying Amaryl MP are taking an important step in managing type 2 diabetes. Finding a reliable, trustworthy source to buy it from is also important, and we hope you'll give Kiwi Drug the opportunity to demonstrate that we are both of those.

Kiwi Drug delivers only authentic medications from authorized manufacturers; our low prices are the result of our low overhead from an online storefront. We're backed by an international network of brick & mortar pharmacies, and are subject to the same regulatory oversight. Your personal data is protected with state-of-the-art security software, and we will not share that information with any third party for any reason.

Clients will need a prescription to buy Amaryl MP. If you don't have one, you're welcome to take advantage of our online doctor services for no additional charge---simply add the product to your cart, initiate checkout, and answer the questions about your medical history and other medications being taken to see if you qualify.

Patients who already have a prescription to buy Amaryl MP will be given options to transfer it to us after completing checkout.

You're welcome to contact us any time if you have any questions or encounter a difficulty with your order.